Comparative salivary gland transcriptomics of sandfly vectors of visceral leishmaniasis
نویسندگان
چکیده
منابع مشابه
Comparative Analysis of Salivary Gland Transcriptomes of Phlebotomus orientalis Sand Flies from Endemic and Non-endemic Foci of Visceral Leishmaniasis
BACKGROUND In East Africa, Phlebotomus orientalis serves as the main vector of Leishmania donovani, the causative agent of visceral leishmaniasis (VL). Phlebotomus orientalis is present at two distant localities in Ethiopia; Addis Zemen where VL is endemic and Melka Werer where transmission of VL does not occur. To find out whether the difference in epidemiology of VL is due to distant composit...
متن کاملApplication of predictive degree day model for field development of sandfly vectors of visceral leishmaniasis in northwest of Iran.
BACKGROUND & OBJECTIVES Temperature plays a significant role in insect's development where a rise in temperature, accelerates the insect's metabolic rates, increases egg production and makes blood feeding more frequent. It also shortens the time period required for the development of pathogens within insects. Visceral leishmaniasis (VL) is one of the most important vector-borne diseases transmi...
متن کاملSalivary Gland Transcriptomes and Proteomes of Phlebotomus tobbi and Phlebotomus sergenti, Vectors of Leishmaniasis
BACKGROUND Phlebotomus tobbi is a vector of Leishmania infantum, and P. sergenti is a vector of Leishmania tropica. Le. infantum and Le. tropica typically cause visceral or cutaneous leishmaniasis, respectively, but Le. infantum strains transmitted by P. tobbi can cause cutaneous disease. To better understand the components and possible implications of sand fly saliva in leishmaniasis, the tran...
متن کاملLeishmaniasis and the Sandfly
Sir,?Much evidence purporting to support the theory that sandflies transmit leishmaniasis has accumulated. This is not surprising for such evidence has been looked for too assiduously and Pasteur's dictum?? Be very careful when you are looking for a thing or you will be sure to find it'?has been frequently ignored in these investigations. Malone and Brooks (1944) gave reasons for believing that...
متن کاملVISCERAL LEISHMANIASIS AS FEVER OF UNKNOWN ORIGIN
Visceral leishmaniasis is the second most common cause of fever of unknown origin in our study. This disease is not common in adults, although it's endemic among the pediatric age group. The majority of the affected individuals were young. High grade spiking fever, chills and splenomegaly were unique findings. Other common findings were neutropenia, anemia, abnormal liver function tests, st...
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ژورنال
عنوان ژورنال: BMC Genomics
سال: 2006
ISSN: 1471-2164
DOI: 10.1186/1471-2164-7-52